Publications

All publications of Oliver Eickelberg at PubMed: Click here..

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Scientific publications of the Lab:

2013:

Kugler JE, Horsch M, Huang D, Furusawa T, Rochman M, Garrett L, Becker L, Bohla A, Holter SM, Prehn C, Rathkolb B, Racz I, Aguilar-Pimentel JA, Adler T, Adamski J, Beckers J, Busch DH, Eickelberg O, Klopstock T, Ollert M, Stoeger T, Wolf E, Wurst W, Yildirim AO, Zimmer A, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Garfinkel B, Orly J, Ovcherenko I, Bustin M.
HMGN Proteins Modulate The Fidelity Of The Cellular Transcriptional Profile In A Tissue And Variant Specific Manner.
J Biol Chem. 2013 Apr 24.

Venit T, Dzijak R, Kalendová A, Kahle M, Rohožková J, Schmidt V, Rülicke T, Rathkolb B, Hans W, Bohla A, Eickelberg O, Stoeger T, Wolf E, Yildirim AÖ, Gailus-Durner V, Fuchs H, de Angelis MH, Hozák P.
Mouse nuclear Myosin I knock-out shows interchangeability and redundancy of Myosin isoforms in the cell nucleus.
PLoS One. 2013 Apr 11;8(4):e61406. doi: 10.1371/journal.pone.0061406. Print 2013.

Karo-Atar D, Moshkovits I, Eickelberg O, Königshoff M, Munitz A.
Paired immunoglobulin-like receptor-B inhibits pulmonary fibrosis by suppressing profibrogenic properties of alveolar macrophages.
Am J Respir Cell Mol Biol. 2013 Apr;48(4):456-64. doi: 10.1165/rcmb.2012-0329OC.

Krauss-Etschmann S, Bush A, Bellusci S, Brusselle GG, Dahlén SE, Dehmel S, Eickelberg O, Gibson G, Hylkema MN, Knaus P, Königshoff M, Lloyd CM, Macciarini P, Mailleux A, Marsland BJ, Postma DS, Roberts G, Samakovlis C, Stocks J, Vandesompele J, Wjst M, Holloway J.
Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease.
Thorax. 2013 Apr;68(4):380-4. doi: 10.1136/thoraxjnl-2012-201902. Epub 2012 Jul 10.

Hoegl S, Meinel FG, Thieme SF, Johnson TR, Eickelberg O, Zwissler B, Nikolaou K.
Worsening respiratory function in mechanically ventilated intensive care patients: feasibility and value of xenon-enhanced dual energy CT.
Eur J Radiol. 2013 Mar;82(3):557-62. doi: 10.1016/j.ejrad.2012.10.029. Epub 2012 Dec 10.

Königshoff M, Saglani S, Marsland BJ, Eickelberg O.
Rebuilding a diseased lung: repair and regeneration.
Eur Respir J. 2013 Mar;41(3):497-9. doi: 10.1183/09031936.00173012. No abstract available.

Behr J, Günther A, Ammenwerth W, Bittmann I, Bonnet R, Buhl R, Eickelberg O, Ewert R, Gläser S, Gottlieb J, Grohé C, Kreuter M, Kroegel C, Markart P, Neurohr C, Pfeifer M, Prasse A, Schönfeld N, Schreiber J, Sitter H, Theegarten D, Theile A, Wilke A, Wirtz H, Witt C, Worth H, Zabel P, Müller-Quernheim J, Costabel U.
[German guideline for diagnosis and management of idiopathic pulmonary fibrosis].
Pneumologie. 2013 Feb;67(2):81-111. doi: 10.1055/s-0032-1326009. Epub 2013 Jan 16. German.

Lenz AG, Karg E, Brendel E, Hinze-Heyn H, Maier KL, Eickelberg O, Stoeger T, Schmid O.
Inflammatory and oxidative stress responses of an alveolar epithelial cell line to airborne zinc oxide nanoparticles at the air-liquid interface: a comparison with conventional, submerged cell-culture conditions.
Biomed Res Int. 2013;2013:652632. doi: 10.1155/2013/652632. Epub 2013 Jan 2.

Meinel FG, Schwab F, Schleede S, Bech M, Herzen J, Achterhold K, Auweter S, Bamberg F, Yildirim AÖ, Bohla A, Eickelberg O, Loewen R, Gifford M, Ruth R, Reiser MF, Pfeiffer F, Nikolaou K.
Diagnosing and mapping pulmonary emphysema on x-ray projection images: incremental value of grating-based x-ray dark-field imaging.
PLoS One. 2013;8(3):e59526. doi: 10.1371/journal.pone.0059526. Epub 2013 Mar 26.

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2012:

Schwab F, Schleede S, Hahn D, Bech M, Herzen J, Auweter S, Bamberg F, Achterhold K, Yildirim AO, Bohla A, Eickelberg O, Loewen R, Gifford M, Ruth R, Reiser MF, Nikolaou K, Pfeiffer F, Meinel FG.
Comparison of Contrast-to-Noise Ratios of Transmission and Dark-Field Signal in Grating-Based x-ray Imaging for Healthy Murine Lung Tissue.
Z Med Phys. 2012 Dec 5. doi:pii: S0939-3889(12)00148-1. 10.1016/j.zemedi.2012.11.003.

Kwapiszewska G, Chwalek K, Marsh LM, Wygrecka M, Wilhelm J, Best J, Egemnazarov B, Weisel FC, Osswald SL, Schermuly RT, Olschewski A, Seeger W, Weissmann N, Eickelberg O, Fink L.
BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension.
Am J Pathol. 2012 Dec;181(6):2018-29. doi: 10.1016/j.ajpath.2012.08.028.

van Rijt SH, Keller IE, John G, Kohse K, Yildirim AÖ, Eickelberg O, Meiners S.
Acute cigarette smoke exposure impairs proteasome function in the lung.
Am J Physiol Lung Cell Mol Physiol. 2012 Nov 1;303(9):L814-23. doi: 10.1152/ajplung.00128.2012.

Meiners S, Eickelberg O.
What shall we do with the damaged proteins in lung disease? Ask the proteasome!
Eur Respir J. 2012 Nov;40(5):1260-8. doi: 10.1183/09031936.00208511.

Schleede S, Meinel FG, Bech M, Herzen J, Achterhold K, Potdevin G, Malecki A, Adam-Neumair S, Thieme SF, Bamberg F, Nikolaou K, Bohla A, Yildirim AÖ, Loewen R, Gifford M, Ruth R, Eickelberg O, Reiser M, Pfeiffer F.
Emphysema diagnosis using X-ray dark-field imaging at a laser-driven compact synchrotron light source.
Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):17880-5. doi: 10.1073/pnas.1206684109.

Thieme SF, Möller W, Becker S, Schuschnig U, Eickelberg O, Helck AD, Reiser MF, Johnson TR.
Ventilation imaging of the paranasal sinuses using xenon-enhanced dynamic single-energy CT and dual-energy CT: a feasibility study in a nasal cast.
Eur Radiol. 2012 Oct;22(10):2110-6. doi: 10.1007/s00330-012-2483-5.

Fuchs H, Gailus-Durner V, Neschen S, Adler T, Afonso LC, Aguilar-Pimentel JA, Becker L, Bohla A, Calzada-Wack J, Cohrs C, Dewert A, Fridrich B, Garrett L, Glasl L, Götz A, Hans W, Hölter SM, Horsch M, Hurt A, Janas E, Janik D, Kahle M, Kistler M, Klein-Rodewald T, Lengger C, Ludwig T, Maier H, Marschall S, Micklich K, Möller G, Naton B, Prehn C, Puk O, Rácz I, Räss M, Rathkolb B, Rozman J, Scheerer M, Schiller E, Schrewe A, Steinkamp R, Stöger C, Sun M, Szymczak W, Treise I, Vargas Panesso IL, Vernaleken AM, Willershäuser M, Wolff-Muscate A, Zeh R, Adamski J, Beckers J, Bekeredjian R, Busch DH, Eickelberg O, Favor J, Graw J, Höfler H, Höschen C, Katus H, Klingenspor M, Klopstock T, Neff F, Ollert M, Schulz H, Stöger T, Wolf E, Wurst W, Yildirim AÖ, Zimmer A, Hrabě de Angelis M.
Innovations in phenotyping of mouse models in the German Mouse Clinic.
Mamm Genome. 2012 Oct;23(9-10):611-22. doi: 10.1007/s00335-012-9415-1.

Meiners S, Eickelberg O.
Next-generation personalized drug discovery: the tripeptide GHK hits center stage in chronic obstructive pulmonary disease.
Genome Med. 2012 Sep 21;4(8):70.

Fernandez IE, Eickelberg O.
New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis.
Lancet. 2012 Aug 18;380(9842):680-8. doi: 10.1016/S0140-6736(12)61144-1.

Seeger W, Welte T, Eickelberg O, Mall M, Rabe KF, Keller B, Winkler S, Koller U.
[The German centre for lung research - translational research for the prevention, diagnosis and treatment of respiratory diseases].
Pneumologie. 2012 Aug;66(8):464-9. doi: 10.1055/s-0032-1310086.

Fernandez IE, Eickelberg O.
The impact of TGF-β on lung fibrosis: from targeting to biomarkers.
Proc Am Thorac Soc. 2012 Jul;9(3):111-6. doi: 10.1513/pats.201203-023AW.

Takenaka S, Möller W, Semmler-Behnke M, Karg E, Wenk A, Schmid O, Stoeger T, Jennen L, Aichler M, Walch A, Pokhrel S, Mädler L, Eickelberg O, Kreyling WG.
Efficient internalization and intracellular translocation of inhaled gold nanoparticles in rat alveolar macrophages.
Nanomedicine (Lond). 2012 Jun;7(6):855-65. doi: 10.2217/nnm.11.152.

Bidmon B, Kratochwill K, Rusai K, Kuster L, Herzog R, Eickelberg O, Aufricht C.
Increased immunogenicity is an integral part of the heat shock response following renal ischemia.
Cell Stress Chaperones. 2012 May;17(3):385-97. doi: 10.1007/s12192-011-0314-2.

Mittal RA, Hammel M, Schwarz J, Heschl KM, Bretschneider N, Flemmer AW, Herber-Jonat S, Königshoff M, Eickelberg O, Holzinger A.
SFTA2--a novel secretory peptide highly expressed in the lung--is modulated by lipopolysaccharide but not hyperoxia.
PLoS One. 2012;7(6):e40011. doi: 10.1371/journal.pone.0040011.

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2011:

Beyerle A, Braun A, Banerjee A, Ercal N, Eickelberg O, Kissel TH, Stoeger T.
Inflammatory responses to pulmonary application of PEI-based siRNA nanocarriers in mice.
Biomaterials. 2011 Nov;32(33):8694-701. doi: 10.1016/j.biomaterials.2011.07.082.

Königshoff M, Schwarz J, Eickelberg O.
Human lung stem cells: oh, the places you'll go!
EMBO Mol Med. 2011 Oct;3(10):575-7. doi: 10.1002/emmm.201100166.

Marsland BJ, Königshoff M, Saglani S, Eickelberg O.
Immune system dysregulation in chronic lung disease.
Eur Respir J. 2011 Sep;38(3):500-1. doi: 10.1183/09031936.00103211.

Zhou Q, Pardo A, Königshoff M, Eickelberg O, Budinger GR, Thavarajah K, Gottardi CJ, Jones J, Varga J, Selman M, Sznajder JI, Raj JU, Zhou G.
Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis.
FASEB J. 2011 Sep;25(9):3032-44. doi: 10.1096/fj.10-177824.

Pullamsetti SS, Savai R, Dumitrascu R, Dahal BK, Wilhelm J, Konigshoff M, Zakrzewicz D, Ghofrani HA, Weissmann N, Eickelberg O, Guenther A, Leiper J, Seeger W, Grimminger F, Schermuly RT.
The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis.
Sci Transl Med. 2011 Jun 15;3(87):87ra53. doi: 10.1126/scitranslmed.3001725.

Dumitrascu R, Kulcke C, Königshoff M, Kouri F, Yang X, Morrell N, Ghofrani HA, Weissmann N, Reiter R, Seeger W, Grimminger F, Eickelberg O, Schermuly RT, Pullamsetti SS.
Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats.
Eur Respir J. 2011 May;37(5):1104-18. doi: 10.1183/09031936.00126010.

Kneidinger N, Yildirim AÖ, Callegari J, Takenaka S, Stein MM, Dumitrascu R, Bohla A, Bracke KR, Morty RE, Brusselle GG, Schermuly RT, Eickelberg O, Königshoff M.
Activation of the WNT/β-catenin pathway attenuates experimental emphysema.
Am J Respir Crit Care Med. 2011 Mar 15;183(6):723-33. doi: 10.1164/rccm.200910-1560OC.

Kilinç E, Schulz H, Kuiper GJ, Spronk HM, Ten Cate H, Upadhyay S, Ganguly K, Stoeger T, Semmler-Bhenke M, Takenaka S, Kreyling WG, Pitz M, Reitmeir P, Peters A, Eickelberg O, Wichmann HE.
The procoagulant effects of fine particulate matter in vivo.
Part Fibre Toxicol. 2011 Mar 15;8:12; author reply 12. doi: 10.1186/1743-8977-8-12.

Wruck CJ, Streetz K, Pavic G, Götz ME, Tohidnezhad M, Brandenburg LO, Varoga D, Eickelberg O, Herdegen T, Trautwein C, Cha K, Kan YW, Pufe T.
Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter.
J Biol Chem. 2011 Feb 11;286(6):4493-9. doi: 10.1074/jbc.M110.162008.

Zakrzewicz D, Zakrzewicz A, Wilker S, Boedeker RH, Padberg W, Eickelberg O, Grau V.
Dimethylarginine metabolism during acute and chronic rejection of rat renal allografts.
Nephrol Dial Transplant. 2011 Jan;26(1):124-35. doi: 10.1093/ndt/gfq392.

Hector A, Kormann MS, Mack I, Latzin P, Casaulta C, Kieninger E, Zhou Z, Yildirim AÖ, Bohla A, Rieber N, Kappler M, Koller B, Eber E, Eickmeier O, Zielen S, Eickelberg O, Griese M, Mall MA, Hartl D.
The chitinase-like protein YKL-40 modulates cystic fibrosis lung disease.
PLoS One. 2011;6(9):e24399. doi: 10.1371/journal.pone.0024399.

Zhang Y, Handley D, Kaplan T, Yu H, Bais AS, Richards T, Pandit KV, Zeng Q, Benos PV, Friedman N, Eickelberg O, Kaminski N.
High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells.
PLoS One. 2011;6(5):e20319. doi: 10.1371/journal.pone.0020319.

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2010:

Königshoff M, Dumitrascu R, Udalov S, Amarie OV, Reiter R, Grimminger F, Seeger W, Schermuly RT, Eickelberg O.
Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention.
Thorax. 2010 Nov;65(11):949-55. doi: 10.1136/thx.2009.134353.

Nikolova S, Guenther A, Savai R, Weissmann N, Ghofrani HA, Konigshoff M, Eickelberg O, Klepetko W, Voswinckel R, Seeger W, Grimminger F, Schermuly RT, Pullamsetti SS.
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis.
Respir Res. 2010 Oct 27;11:146. doi: 10.1186/1465-9921-11-146.

Upadhyay S, Ganguly K, Stoeger T, Semmler-Bhenke M, Takenaka S, Kreyling WG, Pitz M, Reitmeir P, Peters A, Eickelberg O, Wichmann HE, Schulz H.
Cardiovascular and inflammatory effects of intratracheally instilled ambient dust from Augsburg, Germany, in spontaneously hypertensive rats (SHRs).
Part Fibre Toxicol. 2010 Sep 29;7:27. doi: 10.1186/1743-8977-7-27.

Hecker M, Zaslona Z, Kwapiszewska G, Niess G, Zakrzewicz A, Hergenreider E, Wilhelm J, Marsh LM, Sedding D, Klepetko W, Lohmeyer J, Dimmeler S, Seeger W, Weissmann N, Schermuly RT, Kneidinger N, Eickelberg O, Morty RE.
Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension.
Am J Respir Crit Care Med. 2010 Sep 15;182(6):805-18. doi: 10.1164/rccm.200909-1367OC.

Eickelberg O, Laurent G, Nicod LP, Hartl S, Siafakas NM; ad hoc committee.
European Respiratory Society MD PhD programme in respiratory science.
Eur Respir J. 2010 Aug;36(2):229-30. doi: 10.1183/09031936.00046410.

Ask K, Eickelberg O, Gauldie J, Kaminski N, Kolb M.
Have advanced research technologies made real impact on respiratory medicine?
Respirology. 2010 Aug;15(6):876-80. doi: 10.1111/j.1440-1843.2010.01811.x.

Pandit KV, Corcoran D, Yousef H, Yarlagadda M, Tzouvelekis A, Gibson KF, Konishi K, Yousem SA, Singh M, Handley D, Richards T, Selman M, Watkins SC, Pardo A, Ben-Yehudah A, Bouros D, Eickelberg O, Ray P, Benos PV, Kaminski N.
Inhibition and role of let-7d in idiopathic pulmonary fibrosis.
Am J Respir Crit Care Med. 2010 Jul 15;182(2):220-9. doi: 10.1164/rccm.200911-1698OC.

Eickelberg O, Selman M.
Update in diffuse parenchymal lung disease 2009.
Am J Respir Crit Care Med. 2010 May 1;181(9):883-8. doi: 10.1164/rccm.201001-0124UP.

Eickelberg O, Laurent GJ.
The quest for the initial lesion in idiopathic pulmonary fibrosis: gene expression differences in IPF fibroblasts.
Am J Respir Cell Mol Biol. 2010 Jan;42(1):1-2. doi: 10.1165/rcmb.2009-0245ED.

Königshoff M, Eickelberg O.
WNT signaling in lung disease: a failure or a regeneration signal?
Am J Respir Cell Mol Biol. 2010 Jan;42(1):21-31. doi: 10.1165/rcmb.2008-0485TR.